What is Ultherapy Prime? Ultherapy Prime is the latest version of Ultherapy, a non-surgical lifting treatment that uses focused ultrasound to stimulate collagen deep in the skin. Unlike lasers or radiofrequency, Ultherapy works on the SMAS layer—the same layer tightened in facelift surgery—without any incisions. The treatment gradually lifts and tightens sagging areas such as the cheeks, jawline, and neck, and also smooths fine lines around the eyes. Results build naturally o